Services :
 

 
Facility Available :

1. Realtime PCR- Quant studio 5
2. Fluorescence Microscope- DeWinter
3. Geldoc System- Bio-Rad
4. PCR instrument – Proflex

Scope of Activity:

• Diagnostics: Real time PCR test for EGFR exon study and Oncomine BRCA assay GX (DNA) by NGS
• Research: Various projects are being carried out in three major malignancies i.e. Breast Cancer, Oral cancer and lung cancer. The research activities mainly involve studies of stem cell pathways, signal transduction pathways, Genetics, epigenetics, mutational analysis, proteomics and DNA damage and repair mechanism.
• Academics: Faculties of the lab are involved in the lectures, practical and examination duties of M.Sc. cancer biology course and training the DM Oncopathology students for molecular biology techniques.
• Currently two PhD students are registered under Dr. Franky Shah (Guide: Ph.D. (life science)).  

Strength / Workload :

• EGFR exon study :150-160 patients
• Oncomine BRCA Assay GX by NGS: 200- 210 patients

Diagnostic:

• Molecular test for EGFR exon study by Real time PCR for the lung cancer patients
• Oncomine BRCA Assay GX by Next generation sequencing (NGS)

Area of Interest: The group is keenly interested in studying the various stem cell-related pathways and the mechanism for therapy resistance, epigenetics involved in cancer development and progression, molecular pathogenesis of hereditary breast and ovarian cancer, signal transduction pathways and their interactions circuits, and DNA damage and repair mechanism involved in cancer development and advancement